Source: ORPHANET

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7415
Gene Symbol: VCP
VCP 		valosin containing protein 0.469 0.923 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.962 1 0 2008 2020
Entrez Id: 5444
Gene Symbol: PON1
PON1 		paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.929 2 0 2007 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		PPARG coactivator 1 alpha 0.453 0.885 1.00
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.490 None 1.000 1 0 2007 2018
Entrez Id: 25978
Gene Symbol: CHMP2B
CHMP2B 		charged multivesicular body protein 2B 0.543 0.731 4.6E-06
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.680 None 1.000 3 0 2006 2016
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2 		ataxin 2 0.482 0.808 0.85
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.971 1 0 2006 2019
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		TAR DNA binding protein 0.493 0.808 0.99
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.700 None 0.979 1 0 2006 2020
Entrez Id: 1639
Gene Symbol: DCTN1
DCTN1 		dynactin subunit 1 0.597 0.500 8.4E-02
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.909 1 0 2005 2019
Entrez Id: 9217
Gene Symbol: VAPB
VAPB 		VAMP associated protein B and C 0.666 0.423 0.58
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.967 1 0 2004 2019
Entrez Id: 283
Gene Symbol: ANG
ANG 		angiogenin 0.511 0.769 0.29
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 0.959 1 0 2004 2019
Entrez Id: 5630
Gene Symbol: PRPH
PRPH 		peripherin 0.623 0.462 4.8E-14
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 1.000 0 0 2000 2016
Entrez Id: 6647
Gene Symbol: SOD1
SOD1 		superoxide dismutase 1 0.379 0.962 0.18
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.800 strong 0.985 1 0 1993 2020
Entrez Id: 4744
Gene Symbol: NEFH
NEFH 		neurofilament heavy 0.588 0.769 2.7E-12
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 		disease 0.500 None 1.000 1 0 1993 2018